• Are the Relationships of Lean Mass and Fat Mass With Bone Microarchitecture Causal or Due to Familial Confounders? A Novel Study of Adult Female Twin Pairs 

      Bui, Minh; Zebaze, Roger; Li, Shuai; Hopper, John L.; Bjørnerem, Åshild (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-01)
      It is not known whether the relationships of lean mass (LM) and fat mass (FM) with bone microarchitecture and geometry are causal and/or are because of confounders, including familial confounders arising from genetic and environment effects shared by relatives. We tested the hypotheses that: (i) LM is associated with cortical bone traits, (ii) FM is associated with trabecular bone traits, and (iii) ...
    • Is There a Causal Relationship between Physical Activity and Bone Microarchitecture? A Study of Adult Female Twin Pairs 

      Nissen, Frida Igland; Esser, Vivienne F. C.; Bui, Minh; Li, Shuai; Hopper, John L.; Bjørnerem, Åshild Marit; Hansen, Ann Kristin (Journal article; Tidsskriftartikkel, 2023-05-17)
      The reasons for the association between physical activity (PA) and bone microarchitecture traits are unclear. We examined whether these associations were consistent with causation and/or with shared familial factors using a cross-sectional study of 47 dizygotic and 93 monozygotic female twin pairs aged 31–77 years. Images of the nondominant distal tibia were obtained using high-resolutionperipheral ...